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ARABIANBUSINESS Wed, 07 May 2008
The successful treatment of Diabetes has as much to do with lifestyle behaviour and good communication as it does with insulin, according to Diabetes specialist, Professor Tadej Battelino.


"There is good clinical evidence that at every age and every situation the insulin pump is successful, however insulin is only one part of a successful Diabetes management strategy," observed Professor Battelino.

Professor Battelino of the University Medical Centre of Ljubljana in Slovenia was speaking to more than 100 Abu Dhabi-based medical professionals at Imperial College London Diabetes Centre (ICLDC). He stressed the radical developments in insulin pump therapy and importance of carbohydrate counting.

"It is very important to ensure that individual eating patterns are in rhythm with prescribed insulin therapy," he said. Meanwhile, Wafa Ayesh, Head of Clinical Nutrition at Dubai's Rashid Hospital, supported Professor Battelino's observations stressing the importance of carbohydrate counting.

She said that an easy method now assigns each food item with a 'point value' based on the amount of carbohydrates contained, therefore stream-lining the process for the patient. "However, we continue to find that patients are confused about what constitutes a carbohydrate.

"Patients bring me a box and point out that it reads 'sugar free' on it. I have to explain that there are things other than sugar which are carbohydrates, such as potatoes and wheat," said Ms Ayesh.

Professor Battelino confirmed the recently-launched, Internet-based monitoring component of the insulin pump therapy. "This will play a vital role in the treatment of Diabetes as it provides healthcare professionals with direct and up-to-the-minute information, such as blood glucose levels," he concluded.


ARABIANBUSINESS 1 May 2008
Diabetes affects 180 million worldwide and likely to double by 2030; ICLDC continues to drive education and awareness to UAE.


A fatty liver syndrome frequently thought to be the result of an excessive alcohol intake has now been linked to Diabetes, according to Professor Simon Taylor-Robinson, a visiting specialist at Abu Dhabi's Imperial College London Diabetes Centre (ICLDC).

"For a long time doctors have thought that fatty liver condition was linked to high alcohol consumption. "However, the condition is now known as non-alcoholic fatty liver disease and is found to be present in many people living with Diabetes," Professor Taylor-Robinson observed. He went on to explain that the liver tends to respond in the same way, whether the cause is alcohol or Diabetes.

"The nature of the liver is that alcohol-related fatty liver disease is difficult to distinguish from Diabetes-related fatty liver disease," he said. He added that research shows that the rate of non-alcoholic fatty liver disease is increasing in line with the burgeoning growth rate of obesity.

"Non-alcoholic fatty liver disease generally develops slowly and is often associated with Diabetes, insulin resistance and obesity. People who have simple fatty liver in their forties might develop fibrosis or cirrhosis after several years."

However, Professor Taylor-Robinson said that the good news is that recent studies also suggest that liver damage does not have to be permanent. "There is a very good chance that the condition can be reversed in many patients as research has shown that the liver can repair itself, even in the stage of advanced cirrhosis.

In line with the recommended healthy lifestyle treatment for Diabetes, fatty-liver disease also requires patients to adopt a combination of a good diet and regular exercise for the reversal to be successful. The World Health Organization (WHO) estimates that more than 180 million people worldwide have Diabetes and this number is likely to more than double by 2030.

Professor Taylor-Robinson, who was speaking at one of ICLDC's on-going series of specialist lectures, said that Diabetes-related fatty liver too is on the increase worldwide: "It is much more common than originally thought," he concluded.


BBC Mon, 28 Apr 2008 10:54:47 GMT
Imagine an extract from a berry that would make sour things taste sweet and help you lose weight. Then imagine not being allowed to take it.

The world is getting fatter. One billion people are overweight, and 300 million of those are clinically obese.

The search is always on for replacements for those things that, eaten in excess, make us obese - fatty and sugary foods. There is no miracle pill that can replace either. Nearly four decades ago one man came close to providing a tablet that could reduce our love of sugar. In the 1960s, Robert Harvey, a biomedical postgraduate student, encountered the miracle berry, an African fruit which turns sour tastes to sweet.

The FDA, which had previously been very supportive, wrote to Miralin, effectively banning its product. No co-incidence, according to Don Emery.

"I honestly believe that we were done in by some industrial interest that did not want to see us survive because we were a threat. Somebody influenced somebody in the FDA to cause the regulatory action that was taken against us."

The Calorie Control Council, which represents artificial sweetener manufacturers in the US, has failed to respond to questions on the issue.

The Food and Drugs Administration also refused to be interviewed and has indicated that a Freedom of Information (FOI) legislation request to look at the relevant FDA files will not be considered for a year. Robert Harvey had requested the same files over 30 years ago.

"We got back the most redacted information I've ever seen from FOI. Everything was blacked out. There would have been material in the file that would have embarrassed the FDA, I believe."

Faced with this silence, it's virtually impossible to assess what actually happened to prevent the miracle berry's progress to a sugar-free market.

But one thing is certain, it never got the chance to prove whether it really would have provided a miracle in our ever fattening world. And for Robert Harvey, that's the biggest shame of all.

"It was a big loss not only for my employees and shareholders but, even more importantly, for diabetics and other people with special dietary needs. It was tragic."

PRESSTV Wed, 16 Jan 2008
Soda is not considered a health drink as it can make individuals more prone to diseases like obesity, diabetes, cancer and DNA damage.

Each can of soda contains about 10 teaspoons of sugar, 30 to 55 milligrams of caffeine, and is loaded with artificial food colors and sulphites. It is also the largest source of dangerous high-fructose modified corn syrup.

The following shows what happens in the body after drinking a can of soda:

Within the first 10 minutes, 10 teaspoons of sugar hit the system. This is 100 percent of the recommended daily sugar intake. The only reason the overwhelming sweetness does not result in vomiting is because phosphoric acid cuts the flavor.

After 20 minutes, the blood sugar spikes, and the liver responds to the resulting insulin burst by turning massive amounts of sugar into fat. This can later lead to high cholesterol, heart disease, diabetes, weight gain, premature aging and many more negative side effects.

Within 40 minutes, caffeine absorption is complete; the pupils dilate, the blood pressure rises, and the liver releases more sugar into the bloodstream.

After 45 minutes, dopamine production increases. This stimulates the brain's pleasure centers, similar to what happens following heroin use.

After 60 minutes, sugar crash begins.

In the long run the phosphoric acid in soda interferes with the body's ability to use calcium, leading to osteoporosis or softening of the teeth and bones. It can also neutralize the hydrochloric acid in the stomach and cause indigestion.

XINHUANET Mon, 07 Jan 2008 07:21:34 GMT
Study has demonstrated that not getting enough hours of sleep affects the body's ability to manage blood sugar levels and appetite, increasing the risk of obesity and diabetes, U.S. diabetes researchers reported as quoted by media Monday.

The researchers at the University of Chicago Medical Center recruited five men and four women, all lean and healthy, who were between the ages of 20 and 31.

The participants were almost 25 percent less sensitive to insulin after nights of interrupted sleep. As their insulin sensitivity declined, they needed to make more insulin to process the same amount of glucose, or blood sugar.

However their bodies did not make more insulin. As a result, they had 23 percent more blood-glucose, the equivalent of glucose levels in an older adult with impaired glucose tolerance.

According to the researchers, three nights of interrupted sleep effectively gave people in their 20s the glucose and insulin metabolisms of people three times their age. Young adults who do not get enough deep sleep may be increasing their risk of type 2 diabetes.

The researchers suggested that improving the quality of sleep, especially for people as they age or if they are obese, could be an important step in preventing the onset of type 2 diabetes.

They also found that the participants who typically had the least amount of slow-wave sleep during the nights experienced the greatest decline in insulin sensitivity during the study.

This current study provides the first evidence linking poor sleep quality -- specifically the loss of deep or slow-wave sleep -- to increased diabetes risk, said the team.

GUARDIAN Tue, 22 May 2007
A review of the safety of a diabetes drug used by millions of patients was launched in America last night after a study linked it to an increased risk of heart attacks.

Patients using Avandia, the brand name given by GlaxoSmithKline to rosiglitazone, ran a 45% higher risk of a heart attack than those using a placebo or alternative treatment, according to the results of the study published in a leading medical journal.

The US regulator the food and drug administration (FDA) responded by issuing a formal alert to doctors. And congressional leaders in Washington announced that the House oversight committee would hold hearings on GSK's handling of the drug next month.

GSK, the UK's leading pharmaceutical company, disputed the study's findings, arguing it was based on "incomplete evidence and a methodology that the author admits has significant limitations".

Avandia has been taken by more than 6 million people worldwide since it was licensed eight years ago. The drug is one of a group that lower blood glucose levels for people with type 2 diabetes - the late onset form of the disease which is linked to obesity. The FDA warned doctors to be aware of the study published online by the New England Journal of Medicine linking it to heart disease.

The original trials, which led to the drug being approved, did not look at its effect on the heart, say the study's authors, Steven Nissen and Kathy Wolski from the Cleveland clinic in Ohio. Dr Nissen told the Guardian: "I would have preferred it if, right after the drug was launched they'd done a large-scale cardiovascular outcome study. Eight years on, unfortunately we still haven't had a complete one."

In an attempt to establish whether Avandia could cause heart problems, the authors pulled together results of 42 studies into the drug lasting more than 24 weeks.

GSK said it "strongly disagrees" with the findings. The review was not the best way to establish whether a drug has side-effects, it said, because it pulled together information from many trials designed in different ways. The best way to be certain is to run a large, long-term clinical trial looking at risks and benefits in patients. Several of these are in progress and some have been published. One found a small increased heart risk; others found none.

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